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In this work, we propose a multi-layered scaffold made of elastic biodegradable polymer PLCL [1] by salt leaching method [2], which has high porosity at inner layer and high stiffness in outer layer. Before implanting to a damaged position of a patient, scaffolds should be coated with human umbilical vein endothelial cells (HUVECs). (Porous structure is also served as a pathway of sufficient nutrients...
Technologies to develop scaffolds with controlled diameter and high porosity have great significance in tissue engineering. We have fabricated biodegradable 2D and 3D scaffolds with ordered array of pores by casting polymer on self-assembled d-fructose (sugar) microspheres. First, ferrite microparticles were encapsulated in sugar spheres to make them become magnetized. After sieving magnetic sugar...
We have been developing scaffolds of three-dimensional (3D) synthetic vascular prosthesis in tailor-made. Human umbilical vein endothelial cells (HUVECs) attached on the inner surface of the scaffold have anticoagulant effects. Asperity structures of the inner surface are important to cell adhesion. It is important to quantify the inner surface asperity condition of the scaffold by observing HUVECs...
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