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Adult gliomas are divided into isocitrate dehydrogenase (IDH) wild‐type and IDH mutant subtypes according to the new 2021 World Health Organization classification system. However, the local and systemic effects of IDH mutations on primary glioma patients are not well illustrated. Retrospective analysis, immune‐cell infiltration analysis, meta‐analysis, and immunohistochemistry assay were applied in...
Killer cell immunoglobulin‐like receptors (KIRs) are important receptors for regulating the killing of virus‐infected or cancer cells of natural killer (NK) cells. KIR2DS2 can recognize peptides derived from hepatitis C virus (HCV) or global flaviviruses (such as dengue and Zika) presented by HLA‐C*0102 to activate NK cells, and has shown promising results when used for cancer immunotherapy. Here,...
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