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The ability of the κ-opioid receptor agonisttrans -(±)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetami de methanesulfonate (U-50,488) to modulate morphine-induced reward was assessed in preweanling (10- and 17-day-old) and periadolescent (35-day-old) rats using the conditioned place preference paradigm. Conditioning and testing were conducted in a three compartment chamber,...
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