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Repeated caffeine treatment during early postnatal period led to a decreased sensitivity to convulsant action of drugs interfering with inhibitory systems. To know if it is a general effect we studied convulsant action of agonists of glutamate receptors N-methyl-d-aspartate (NMDA) and kainic acid (KA). Early (the first day after the last injection) and delayed (at postnatal day (P) 25) consequences...
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