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Ultrasound (US) Doppler spectrograms have been widely used for diagnosing vascular obstructions. This paper presents an Android smartphone based new approach for detecting the blood flow condition based on the US Doppler spectrogram images. A set of 59 spectrograms acquired from a US Doppler system is processed to extract features, and these non-redundant features are fed into a supervised classifier...
Eukarytotic cells have developed a highly conserved network of processes to ensure that the damaged genome is repaired before replication or mitotic segregation. This protective mechanism is essential for maintaining genomic integrity and stability, cell viability, and prevention of mutations. The drugs used in the treatment of human malignancies are invariably genotoxic, and their effectiveness is...
Base excision repair (BER) is an evolutionarily conserved process for maintaining genomic integrity by eliminating several dozen altered (oxidized, deaminated or alkylated) or inappropriate bases that could be mutagenic. These base lesions are generated endogenously or induced by various genotoxicants, including reactive oxygen species (ROS), reactive nitrogen species (RNS) or alkylating agents. BER...
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