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Changes in cerebral cytochrome oxidase (COX) activity, nitric oxide (NO)–cyclic GMP (cGMP) pathway and cholinergic muscarinic receptors (MRs) have been reported in rodents acutely exposed to carbon monoxide (CO). These endpoints measurable in lymphocytes may serve as peripheral markers of CO neurotoxicity.The early and delayed effects of repeated and acute in vivo CO inhalation were investigated on...
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