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Objective
Serotonin (5‐HT) infusion in vivo causes hypotension and a fall in total peripheral resistance. However, the vascular segment and the receptors that mediate this response remain in question. We hypothesized that 5‐HT7 receptors mediate arteriolar dilation to 5‐HT in skeletal muscle microcirculation.
Methods
Cremaster muscles of isoflurane‐anesthetized male Sprague‐Dawley rats were prepared...