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We developed a micro-TAS system that uses magnetic wires instead of the conventional beads as the carrier to improve reaction efficiency. Magnetic wire 2.0 mm×74 μm×20 μm was fabricated by wet etching. The wires were introduced into a droplet immersed in silicone oil, and they were manipulated by the magnetic force of a moving magnet. The wires were successfully bundled for transportation through...
A pen-shaped platform that is similar to a mechanical pencil was proposed for producing the portable biochemical reaction system presented in previous work. The key component, the sample introduction unit, in the system was proposed in this work. The unit was fabricated by using a heat shrinkable tube. The sample droplet with the volume ranging from 6 to 36 l was successfully introduced into the unit...
We newly introduced a pen-shaped platform like a mechanical pencil, in which an inchworm motion is used to transport the cylinder-shaped reaction unit, to produce a portable biochemical reaction system. The specifications were decided for an application to blood analysis, and the reaction unit was fabricated. The outer diameter and length of the unit were 7.0 and 80.0 mm. The mechanical pencil device...
We have previously proposed a magnetic bead handling mechanism for micro-total-analysis-systems and have developed a palmtop-sized biochemical analysis system. Appropriate agitation is one of the crucial issues in micro-meter-sized fluidic systems. We investigated the agitation produced by using multilayered flat coils and magnetic beads. The beads were magnetically agitated inside the droplet by...
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