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To study the long-term changes induced in immature rat cortical neuronal cultures by transient exposure to an Mg 2+ -free treatment, at cultured day 6, cells were assigned into three groups, based on the mediums they were transiently exposed to as follows: control group 1 (CONT1) was exposed to Dulbecco's Modified Eagle's Medium (DMEM), control group 2 was exposed to a physiological solution...
For the purpose of investigating the long-term effects of seizures in neonatal rats on spatial learning ability and N-methyl-d-aspartate (NMDA) receptor expression in adult rat brain, a seizure was induced by inhalant flurothyl daily in neonatal Wistar rats from postnatal day 6 (P6). The authors assigned six rats each averagely into the single-seizure group, the recurrent-seizure group (seizures induced...
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