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Electroacupuncture (EA) at the Neiguan–Jianshi acupoints (P5–P6, overlying the median nerve) attenuates sympathoexcitatory reflexes probably through the opioid system. The arcuate nucleus (ARC) within hypothalamus is an important brain area that produces opioid peptides. Physiological studies have demonstrated that the predominant response to EA is excitation in the ARC and that excitatory projections...
Our previous studies have demonstrated that stimulation of cardiac sympathetic afferents activates neurons in the parabrachial nucleus (PBN), a region known to play a role in central integration of cardiovascular autonomic reflexes. However, phenotypes of these activated neurons have not been well identified. Glutamate, an important excitatory neurotransmitter in the brain, is involved in PBN-mediated...
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