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The dose- and time-dependent effects ofendoscopic sclerotherapy on luminal cross-sectional areaand wall distensibility were studied in pigs at 5 and 12cm proximal to the gastroesophageal junction by means of impedance planimetry. Sixteen healthyanimals underwent two sessions of endoscopicsclerotherapy two weeks apart with injections of either5 or 10 ml of 1% Polidocanol in the distal 7 cm of the esophagus...
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