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In this work, we developed a simple and sensitive method for the detection of cysteine (Cys) by employing terbium ion (Tb3+)-promoted G-qudraplex (G4/Tb) as a luminescent probe, which is based on Ag+-mediated conformational change of G4/Tb. Due to Ag+ is able to compete with Tb3+ to bind guanine at G4, the presence of Ag+ can lead to the formation of G4/Tb–Ag+ complex and disrupt the structure of...
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