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Background
Orgasmic phase disorders in men worsen the burden of erectile dysfunction on sexual satisfaction.
Objectives
To investigate the prevalence of and predictors of unreported orgasmic phase disorder in a cohort of men looking for their first urological assessment for new‐onset erectile dysfunction in a real‐life setting.
Materials and methods
Data from 1107 heterosexual, sexually active...
Background
Recurrent pregnancy loss and unexplained infertility are the current indications to test sperm DNA fragmentation according to the European Association of Urology Guidelines on sexual and reproductive health.
Objective
To identify a novel and better performing model to diagnose primary infertile men presenting with altered sperm DNA fragmentation and to outline its predictive ability...
Background
The atherosclerotic cardiovascular disease risk score is a validated algorithm predicting an individual's 10‐year risk of developing acute cardiovascular events (cardiovascular disease). Patients who suffer from arteriogenic erectile dysfunction are susceptible to developing cardiovascular disease in the future.
Objectives
To apply the atherosclerotic cardiovascular disease score at...
Background
Infertile men have a worse overall health status than their fertile counterparts.
Objective
We aimed to (1) compare kidney function in men presenting for primary couple's infertility with that of fertile men and (2) assess kidney function impairment toward sperm quality in infertile men.
Materials and methods
In this case–control study, 387 consecutive white‐European infertile men...
Background
Peyronie's disease (PD) has a huge impact on patients’ physical and psychological wellbeing.
Objectives
To investigate whether patients’ age has an impact on PD symptomatic burden at first presentation.
Materials and methods
Data from 129 consecutive heterosexual patients seeking first medical attention for PD at a single andrological tertiary‐referral centre were collected. All patients...
Background
Peyronie's disease (PD) is a fibrosing disorder of the penis resulting in plaque formation and penile deformity that negatively affect sexual and psychosocial function of patients. A multifactorial etiology of PD is assumed with diabetes mellitus (DM) being a potential risk factor.
Objectives
The aim of this narrative review was to investigate diabetes role in PD pathophysiology, diagnosis,...
Objectives
To systematically review the literature to determine the benefits and harms of the surgical techniques used for the correction of adult‐acquired buried penis (AABP).
Materials and methods
The systematic review was registered in the PROSPERO database (CRD42021267440) and conducted according to the Preferred Reporting Items for Systematic Reviews and Meta‐analyses (PRISMA) guidelines....
Background
The identification of biomarkers correlated with coronavirus disease 2019 (COVID‐19) outcomes is a relevant need for clinical management. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection is characterized by elevated interleukin (IL)‐6, IL‐10, HLA‐G, and impaired testosterone production.
Objectives
We aimed at defining the combined impact of sex hormones, interleukin‐10,...
Background
Male patients with COVID‐19 have been found with reduced serum total testosterone (tT) levels and with more severe clinical outcomes.
Objectives
To assess total testosterone (tT) levels and the probability of recovering eugonadal tT levels during a minimum 12‐month timespan in a cohort of men who have been followed over time after the recovery from laboratory‐confirmed COVID‐19.
Materials...
Background
Alfa‐fetoprotein (AFP) is a serum glycoprotein highly produced during fetal development. While AFP synthesis drops dramatically after birth, AFP production only persists or returns under specific pathological condition.
Objective
We sought to investigate the rate of and the potential meaning of high AFP serum levels in men seeking first medical attention for couple's primary infertility...
Background
Penile prosthesis implantation has been associated with overall good functional outcomes. Of relevance, some patients reported higher level of satisfaction and quality of life.
Aim
We investigated the profile of the patients who may benefit the most from penile prosthesis implantation.
Materials and methods
Data from a national multi‐institutional registry of penile prostheses including...
Background
Erectile dysfunction aetiology has been historically identified as organic, psychogenic and mixed.
Objectives
To stratify and compare a cohort of patients seeking medical help for erectile dysfunction for the first time according to the newly proposed binary classification of the European Association of Urology guidelines: ‘primary organic’ versus ‘primary psychogenic’.
Materials and...
Background
In 2021, the World Health Organization (WHO) has provided the latest update on processing and evaluating semen analysis.
Objectives
To assess (i) the rate of discordance in semen parameters categorization across three different WHO reference values (namely WHO21, 2010 and 1999) and (ii) the clinical differences among discordant semen analyses from a cohort of primary infertile men.
...
Background
Male factor contributes to up to 50% of cases of couples experiencing infertility. Cannabis is one of the most commonly used recreational drugs, and its effects on the reproductive system have been largely debated in the literature.
Objectives
The aim of this study is to evaluate the effect of recreational cannabis use on total T (tT) levels, gonadal status, and sperm parameters in a...
Background
A severe male infertility factor has been associated with both lower health status and increased mortality in infertile men.
Objectives
To investigate reproductive factors associated with health status impairment in infertile men over a 10‐year time frame since the first clinical evaluation.
Materials and methods
Data from 899 infertile men were analysed at baseline between 2003 and...
Background
Hyaluronic acid is a glycosaminoglycan widely used in the fields of orthopedics, ophthalmology, and aesthetic medicine due to its significant ability to reduce the synthesis of pro‐inflammatory proteins and its activity against oxidative stress, a feature of many degenerative illnesses.
Objectives
The objective of the present review is to provide a comprehensive narrative review of the...
Background
Circulating testosterone levels have been found to be reduced in men with severe acute respiratory syndrome coronavirus 2 infection, COVID‐19, with lower levels being associated with more severe clinical outcomes.
Objectives
We aimed to assess total testosterone levels and the prevalence of total testosterone still suggesting for hypogonadism at 7‐month follow‐up in a cohort of 121 men...
Background
The EAU guidelines on male sexual and reproductive health state that both partners of the infertile couple should undergo simultaneous investigation.
Objectives
To assess the prevalence and the characteristics of infertile men who were referred for an andrological evaluation after failed attempts of Assisted Reproductive Technology (ART) with those who were evaluated at the beginning...
In the present study, we aimed to evaluate the association between asexual trait, erectile dysfunction (ED) and porn addiction in a community sample of young men. Between August 2019 and October 2019, a total of 559 young male adults were subjected to an online survey sponsored by social networks with the aim of assessing their sexual habits. The following questionnaires were administered: The International...
Background
Circulating androgens could have a relevant pathobiological role in clinical outcomes in men with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection (COVID‐19).
Objectives
We aimed to assess: (a) circulating sex steroids levels in a cohort of 286 symptomatic men with laboratory‐confirmed COVID‐19 at hospital admission compared to a cohort of 281 healthy men; and (b)...
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