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A new 2H-tetrahydropyran derivative, 6-epi-goniothalesdiol A (1), together with nine known styryllactones (2–10) and five known aristolactams (11–15) were isolated from the bark of Goniothalamus elegants Ast. The structures were elucidated by spectroscopic methods. The isolated compounds were evaluated for their cytotoxicity toward the KB, MCF7 and NCI-H187 cell lines as well as antimalarial and antimycobacterial...
Nine linear C23 and C21 acetogenins, named cananginones A–I (1–9), were isolated from stem bark of Cananga latifolia. Their structures were established by spectroscopic methods. These compounds showed cytotoxicity against three cancer cell lines (KB, MCF7 and NCI-H187) with IC 50 values in the range 16.6–129.7μM. Only 5 showed weak antimalarial activity against Plasmodium falciparum. In addition,...
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