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A 30 kDa β-galactose-specific lectin named CVL was isolated from the polychaete marine worm Chaetopterus variopedatus (Annelida) and its anti-HIV-1 activity in vitro was determined. Results showed that CVL inhibited cytopathic effect induced by HIV-1 and the production of viral p24 antigen. The EC 50 values were 0.0043 and 0.057 μM, respectively. Time-of-addition analysis of anti-HIV-1 activity...
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