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BACKGROUND:Pathologic and genetic data suggest that epithelial ovarian cancer may consist of indolent and aggressive phenotypes. The objective of the current study was to estimate the impact of a 2‐phenotype paradigm of epithelial ovarian cancer on the mortality reduction achievable using available screening technologies.
METHODS:The authors modified a Markov model of ovarian cancer natural history...
Ovarian cancer is a leading cause of cancer-related deaths among women. Given the low prevalence of this disease, the effectiveness of screening strategies has not been established. We wished to estimate the clinical impact and cost-effectiveness of potential screening strategies for ovarian cancer using population-specific data.A Markov state transition model to simulate the natural history of ovarian...
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