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It is widely recognized that Sir Joseph Barcroft (1872–1947) laid the modern methodological foundation for the study of the mammalian fetus. After studying high-altitude physiology for decades, Barcroft, at age 60, turned his attention to the physiology of the mammalian fetus to learn how it develops in an environment of extremely low oxygen tension, or as he put it, “while living on Mt. Everest in-utero...
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