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PURPOSE/OBJECTIVE: To encourage tonsillectomy in the systematic evaluation of patients diagnosed with metastatic squamous cell carcinoma to the upper neck from unknown head and neck primary (SCCA unknown H&N primary). To examine the impact of finding occult tonsil cancer on subsequent therapy, particularly radiation field design.MATERIALS & METHODS: The medical records for all patients diagnosed...
Purpose: These preclinical studies were carried out to examine the potential of the antiproliferative polyamine analog 1,19-bis-(ethylamino)-5,10,15-triazanonadecane (BE-4-4-4-4) to serve as a therapy adjuvant to radiation for patients with rapidly dividing tumors of the head and neck (H&N).Methods and Materials: Cytostatic and cytotoxic effects of this polyamine analog were investigated in three...
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