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Aims There are no studies directly comparing self‐administration of methamphetamine and d‐amphetamine by humans. This study compared intranasal methamphetamine‐ and d‐amphetamine self‐administration and characterized the mood, performance and physiological effects produced by the drugs.
Design A randomized, double‐blind, placebo‐controlled, cross‐over study.
Setting An out‐patient research unit...
Rationale Despite their chemical similarities, methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) produce differing neurochemical and behavioral responses in animals. In humans, individual studies of methamphetamine and MDMA indicate that the drugs engender overlapping and divergent effects; there are only limited data comparing the two drugs in the same individuals. Objectives This study...
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