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Background Sarcomatoid renal cell cancer (RCC) is a distinct histological variant of RCC that is associated with rapid progression and a poor prognosis. The optimal treatment for patients with sarcomatoid RCC remains to be defined. Gemcitabine plus doxorubicine (GD) has shown some efficacy, however durability of response is limited. We carried out a prospective, open-label study to investigate the...
Mit den Tyrosinkinase-Inhibitoren Sunitinib und Sorafenib stehen 2 effektive Angiogenese-Inhibitoren zur Therapie des metastasierten Nierenzellkarzinoms zur Verfügung. Bei der notwendigen chronischen Verwendung dieser, einer neuen Substanzklasse zuzuordnenden Medikamente treten Nebenwirkungen auf, die unter Umständen eine langfristige Therapie erschweren oder verhindern können. Die meisten Nebenwirkungen...
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