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Casomokinin L (Tyr-Pro-Phe-Pro-Pro-Leu), a derivative of β-casomorphin and casoxin D, showed endothelium-dependent vasorelaxing activity on the canine mesenteric artery (EC 50 = 7 10 -8 M). This relaxing activity was partly blocked by 10 -5 M NAME (nitric oxide synthase inhibitor), and the inhibition by NAME was restored by addition of 10 -4 ...
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