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BackgroundIgE antibodies specific for the major birch pollen allergen frequently cross‐react with Bet v 1 homologous food proteins, for example Cor a 1 in hazelnut and Mal d 1 in apple. Specific immunotherapy with birch pollen (BP‐SIT) induces IgG4 antibodies that inhibit IgE binding to Bet v 1. However, information on cross‐reactivity of BP‐SIT‐induced Bet v 1‐specific IgG4 antibodies with food allergens...
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