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The toxicity of 30 binary combinations of 10 soft electrophiles was examined in Microtox using dose–response curve (DRC) analysis. Chemicals from three groups of soft electrophiles—vinyl Michael acceptors (I—react with a thiol group), dicarbonyl reactive agents (II—react with a primary amine), and α-haloactivation compounds (III—react with a thiol group)—were selected for testing to evaluate the relationship...
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