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The mammalian Pre‐B cell leukaemia transcription factors 1–4 (PBX1‐4) constitutes the PBC class of the homeodomain (HD)‐containing proteins, which play important roles in diverse developmental processes. The functions and the underlying molecular mechanisms of PBX1‐3 but not PBX4 have been extensively studied, and they have been reported to direct essential morphogenetic processes and organogenesis...
Objectives
Pre‐eclampsia is a leading cause of morbidity and mortality during pregnancy. Although the two forms of this disorder, early‐ (EOPE) and late‐onset of pre‐eclampsia (LOPE) are different, the underlying pathology remains elusive. We aim to unravel the difference and to identify novel biomarkers for EOPE and LOPE.
Materials and Methods
A complete comparison of both placental and peripheral...
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