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Rationale A positron emission tomography (PET) study of dopamine D2 receptor occupancy was conducted to support a rational dose selection for clinical efficacy studies with lurasidone, an atypical antipsychotic that was approved for the treatment of schizophrenia by the FDA in late 2010. Objectives To determine the dopamine D2 receptor occupancy of lurasidone in the ventral striatum, putamen and...
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