Search results for: Paul S. Haber

Items from 1 to 20 out of 68 results

article

Prevalence and factors associated with polydrug use among clients seeking treatment for alcohol misuse

Samuel Lawson, Jamie Bryant, Megan Freund, Joshua Dizon, more

Drug and Alcohol Review > 43 > 5 > 1194 - 1203

Introduction The aim of this paper was to examine the client and psychosocial characteristics associated with polydrug use in patients with alcohol misuse as their primary drug of concern (PDC) seeking treatment from substance use treatment centres. Methods Self‐report surveys were undertaken with clients attending 1 of 34 community‐based substance use treatment centres across Australia with alcohol...

article

All‐cause and liver‐related mortality risk factors in excessive drinkers: Analysis of data from the UK biobank

John B. Whitfield, Devanshi Seth, Timothy R. Morgan, GenomALC Consortium, more

Alcoholism: Clinical and Experimental Research > 46 > 12 > 2245 - 2257

Background High alcohol intake is associated with increased mortality. We aimed to identify factors affecting mortality in people drinking extreme amounts of alcohol. Methods We obtained information from the UK Biobank on approximately 500,000 participants aged 40–70 years at baseline assessment in 2006–2010. Habitual alcohol intake, lifestyle and physiological data, laboratory test results, and...

article

Management of alcohol and other drug issues in Special Health Accommodation during the COVID‐19 Delta variant outbreak in Sydney, 2021

Emily Nash, Emily Walker, Joshua Watt, Alena Sannikova, more

Drug and Alcohol Review > 41 > 6 > 1319 - 1321

article

The impact of a 24‐hour syringe dispensing machine on a face‐to‐face needle and syringe program and targeted primary healthcare clinic

Natalia Uthurralt, Anica McGlinn, Martin O'Donnell, Paul S. Haber, more

Australian and New Zealand Journal of Public Health > 46 > 4 > 524 - 526

Objective: Automatic syringe dispensing machines (ADM) have become an important adjunct to Australia's needle and syringe programs (NSP). However, concerns that they reduce face‐to‐face contact with health staff and other health interventions remain. We examined changes in the number of needle/syringes dispensed at an ADM and occasions of service at a co‐located face‐to‐face NSP and targeted primary...

article

Daily experiences of hangover severity and food consumption in young adults

Kirsten C. Morley, Warren B. Logge, Benjamin C. Riordan, Sean Brannon, more

British Journal of Health Psychology > 27 > 2 > 468 - 483

Objectives Our aim was to determine whether alcohol hangover is associated with eating unhealthy foods (hot chips, soft drink) or healthy foods (fruit, vegetables). Design Daily diary study across 13 days (micro‐longitudinal design). Methods We examined a sample of 605 young adults (71% women; ages 17–25; mean age 19.91 [SD 1.86] years) who completed daily diaries in the university community...

article

Support for Aboriginal health services in reducing harms from alcohol: 2‐year service provision outcomes in a cluster randomized trial

Monika Dzidowska, K. S. Kylie Lee, James H. Conigrave, Timothy A. Dobbins, more

Addiction > 117 > 3 > 796 - 803

Background and aims There is a higher prevalence of unhealthy alcohol use among Indigenous populations, but there have been few studies of the effectiveness of screening and treatment in primary health care. Over 24 months, we tested whether a model of service‐wide support could increase screening and any alcohol treatment. Design Cluster‐randomized trial with 24‐month implementation (12 months...

article

Should we be using e‐vouchers to compensate research participants? Acceptability among opioid agonist treatment clients

Daniel T. Winter, Natalie White, Brennan Geiger, Paul S. Haber, more

Drug and Alcohol Review > 40 > 7 > 1356 - 1357

article

Are bottle shops using Twitter to increase advertising or encourage drinking during COVID‐19?

Daniel T. Winter, Brennan Geiger, Kirsten Morley, James Conigrave, more

Australian and New Zealand Journal of Public Health > 45 > 4 > 391 - 393

Objective: Preliminary reports suggested that liquor retailers used COVID‐19 to promote alcohol through sponsored posts on Facebook and Instagram. To further understand the advertising practices during this period, we aimed to determine whether packaged liquor retailers increased their posts during COVID‐19 or used COVID‐19 to promote alcohol on Twitter. Methods: ‘Tweets’ (Twitter posts) from all...

article

Support can increase use of the AUDIT‐C in Australian Aboriginal Community Controlled Health Services: a cluster randomized trial

James H. Conigrave, Kristie H. Harrison, K. S. Kylie Lee, Timothy A. Dobbins, more

Addiction > 116 > 9 > 2304 - 2315

Background and Aims Unhealthy alcohol consumption is a key concern for Aboriginal and Torres Strait Islander (‘Indigenous’) communities. It is important to identify and treat at‐risk drinkers, to prevent harms to physical or social wellbeing. We aimed to test whether training and support for Aboriginal Community Controlled Health Service (ACCHS) staff would increase rates of alcohol screening and...

article

Genome‐wide Association Study and Meta‐analysis on Alcohol‐Associated Liver Cirrhosis Identifies Genetic Risk Factors

Tae‐Hwi Schwantes‐An, Rebecca Darlay, Philippe Mathurin, Steven Masson, more

Hepatology > 73 > 5 > 1920 - 1931

Background and Aims Only a minority of heavy drinkers progress to alcohol‐associated cirrhosis (ALC). The aim of this study was to identify common genetic variants that underlie risk for ALC. Approach and Results We analyzed data from 1,128 subjects of European ancestry with ALC and 614 heavy‐drinking subjects without known liver disease from Australia, the United States, the United Kingdom, and...

article

Alcohol use disorder and the gut

Paul S. Haber, Nicholas C. Kortt

Addiction > 116 > 3 > 658 - 667

Acute and chronic gastrointestinal problems are common in the setting of excessive alcohol use, and excessive alcohol use is associated with injury to all parts of the gastrointestinal tract. There is mounting evidence of gastrointestinal injury and increased cancer risk even from moderate alcohol consumption. The major causes of alcohol‐related morbidity and mortality within the gastrointestinal...

article

Baclofen modulates cardiovascular responses to appetitive cues in treatment‐seeking alcohol use disorder individuals

Warren B. Logge, Andrew J. Baillie, Paul S. Haber, Kirsten C. Morley

Human Psychopharmacology: Clinical and Experimental > 35 > 2 > n/a - n/a

Objective To assess whether baclofen‐treated alcohol dependent participants show different subjective and psychophysiological responses to appetitive cues during an alcohol cue reactivity task compared to placebo, and whether these responses are associated with prospective drinking outcomes. Methods Forty‐two alcohol dependent participants (placebo: n = 12, low‐dose baclofen [30 mg/day] n = 18,...

article

Brain GABA levels are reduced in alcoholic liver disease: A proton magnetic resonance spectroscopy study

Kirsten C. Morley, Jim Lagopoulos, Warren Logge, Andrew Baillie, more

Addiction Biology > 25 > 1 > n/a - n/a

Background and aims Baclofen, a selective γ‐aminobutyric acid (GABA)_B receptor agonist, has emerged as a potential treatment for alcohol use disorder with much unexplained variation in response to treatment efficacy and dose regimen. Several positive studies include patients with alcoholic liver disease (ALD) and/or history of heavy drinking. The aim of this paper was to examine the association of...

article

Impact of acutely behavioural disturbed patients in the emergency department: A prospective observational study

Matthew Oliver, Aaron A Adonopulos, Paul S Haber, Michael M Dinh, more

Emergency Medicine Australasia > 31 > 3 > 387 - 392

Objective The present study describes patients with acute behavioural disturbance presenting to the ED, the impact they have on the department and any complications that occur. Methods We performed a prospective observational study of adult patients (>17 years old) requiring parenteral sedation for acute behavioural disturbance over a 13 month period. Demographic data, mode of arrival, indication,...

article

Cannabidiol (CBD) content in vaporized cannabis does not prevent tetrahydrocannabinol (THC)-induced impairment of driving and cognition

Thomas R. Arkell, Nicholas Lintzeris, Richard C. Kevin, Johannes G. Ramaekers, more

Psychopharmacology > 2019 > 236 > 9 > 2713-2724

Background The main psychoactive component of cannabis, delta-9-tetrahydrocannabinol (THC), can impair driving performance. Cannabidiol (CBD), a non-intoxicating cannabis component, is thought to mitigate certain adverse effects of THC. It is possible then that cannabis containing equivalent CBD and THC will differentially affect driving and cognition relative to THC-dominant cannabis. Aims The...

article

Identification of smoking status in the Census is needed, but what about the healthcare system?

Louise Ross, Paul S. Haber, Carolyn A. Day

Australian and New Zealand Journal of Public Health > 43 > 1 > 96 - 96

article

Moderation of baclofen response by a GABA_B receptor polymorphism: results from the BacALD randomized controlled trial

Kirsten C. Morley, Natasha Luquin, Andrew Baillie, Isabel Fraser, more

Addiction > 113 > 12 > 2205 - 2213

Background and Aims Baclofen has been shown to reduce alcohol consumption in alcohol‐dependent individuals, but there is marked heterogeneity in response. An association between GABBR1 rs29220 and alcohol dependence has been demonstrated previously. The present study evaluated whether the response to baclofen is moderated by a single nucleotide polymorphism (rs29220) in the GABAB receptor subunit...

article

Topiramate versus naltrexone for alcohol use disorder: study protocol for a genotype-stratified, double-blind randomised controlled trial (TOP study)

Kirsten C. Morley, Henry R. Kranzler, Natasha Luquin, Andrew Baillie, more

Trials > 2018 > 19 > 1 > 1-10

Background Current treatments for alcohol use disorders have limited efficacy and there is a high degree of variability in treatment response. In a randomised, placebo-controlled clinical trial, there was a large effect size for topiramate in people homozygous for the GRIK1 rs2832407*C allele. The primary aim of the TOP study is to examine prospectively the therapeutic and cost-effectiveness of topiramate...

article

Vertical transmission of hepatitis C: Testing and health‐care engagement

Sharon Reid, Carolyn A Day, David G Bowen, Jeannie Minnis, more

Journal of Paediatrics and Child Health > 54 > 6 > 647 - 652

Aim To investigate hepatitis C virus (HCV) testing patterns and engagement with health care for women positive for HCV antibodies (anti‐HCV) in pregnancy and their children through pregnancy and the first 2 years of the child's life. Methods At a large inner‐city Australian hospital from 2010 to 2012, anti‐HCV positive pregnant women were recruited into a cohort study from pregnancy to 2 years...

article

Pharmacotherapy for Alcohol Use Disorder in the Context of Liver Disease

Ted M. Stoklosa, Kirsten C. Morley, Anastasia Volovets, Paul S. Haber

Current Addiction Reports > 2018 > 5 > 2 > 287-296

Purpose Alcohol consumption is a leading cause of morbidity and mortality in our society and alcohol-related liver disease is a major contributor to this. Abstinence is the most important treatment goal for patients with alcohol-related liver disease and appropriate pharmacotherapy can help to achieve this. Recent findings There are a number of established and emerging pharmacotherapies for the...

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INFONA - science communication portal

Search results for: Paul S. Haber

Prevalence and factors associated with polydrug use among clients seeking treatment for alcohol misuse

All‐cause and liver‐related mortality risk factors in excessive drinkers: Analysis of data from the UK biobank

Management of alcohol and other drug issues in Special Health Accommodation during the COVID‐19 Delta variant outbreak in Sydney, 2021

The impact of a 24‐hour syringe dispensing machine on a face‐to‐face needle and syringe program and targeted primary healthcare clinic

Daily experiences of hangover severity and food consumption in young adults

Support for Aboriginal health services in reducing harms from alcohol: 2‐year service provision outcomes in a cluster randomized trial

Should we be using e‐vouchers to compensate research participants? Acceptability among opioid agonist treatment clients

Are bottle shops using Twitter to increase advertising or encourage drinking during COVID‐19?

Support can increase use of the AUDIT‐C in Australian Aboriginal Community Controlled Health Services: a cluster randomized trial

Genome‐wide Association Study and Meta‐analysis on Alcohol‐Associated Liver Cirrhosis Identifies Genetic Risk Factors

Alcohol use disorder and the gut

Baclofen modulates cardiovascular responses to appetitive cues in treatment‐seeking alcohol use disorder individuals

Brain GABA levels are reduced in alcoholic liver disease: A proton magnetic resonance spectroscopy study

Impact of acutely behavioural disturbed patients in the emergency department: A prospective observational study

Cannabidiol (CBD) content in vaporized cannabis does not prevent tetrahydrocannabinol (THC)-induced impairment of driving and cognition

Identification of smoking status in the Census is needed, but what about the healthcare system?

Moderation of baclofen response by a GABA_B receptor polymorphism: results from the BacALD randomized controlled trial

Topiramate versus naltrexone for alcohol use disorder: study protocol for a genotype-stratified, double-blind randomised controlled trial (TOP study)

Vertical transmission of hepatitis C: Testing and health‐care engagement

Pharmacotherapy for Alcohol Use Disorder in the Context of Liver Disease

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