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The mechanisms by which exercise affects atherosclerotic plaque stability remain incompletely understood. We evaluated the effects of two training protocols on both atherosclerotic plaque structure and the signaling pathways involved in plaque rupture.Male low-density lipoprotein (LDL) receptor knockout mice were fed a high-fat, high-cholesterol diet (HFD). One group was subjected to moderate exercise...
β-Adrenoceptor-mediated relaxation of guinea-pig taenia caecum was investigated by studying the effects of BRL37344, CGP12177 and norepinephrine. These drugs caused graded relaxation of the guinea-pig taenia caecum. The concentration-response curves for these drugs were unaffected by propranolol, atenolol, butoxamine, prazosin, yohimbine and phentolamine. Bupranolol produced shifts of the concentration-response...
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