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Most studies of dexamethasone (DXN) effects on experimental glioma have used doses 10–500 higher (on mg/kg basis) than those used for patients with brain tumour. The relevance of findings to patients with glioma are therefore uncertain. In order to eval uate the effects of clinical doses of DXN (0.22mg kg−1day−1) on the pathophysiology of an experimental glioma we have treated rodents with established...
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