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Cells of the E. coli mutant EP432, which lacks the two Na + /H + antiporters, NhaA and NhaB, have been reported to have an impaired sodium transport activity (Harel-Bronstein et al. (1995) J. Biol. Chem. 270, 3816-3822). Here we report that active transport of Na + in EP432 cells can be restored to wild-type levels, either by a high K + concentration or by an increase...
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