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Peripheral serotonin (5‐HT) has been involved in adverse cardiac remodeling and valve fibrosis. The peripheral levels of 5‐HT mainly depend on its release from activated platelets and degradation by monoamine oxidase A (MAO‐A). The SERAOPI study investigated the relationship between arterial serotoninergic system, degree of platelet activation and cardiac remodeling, in patients with aortic valve...
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