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In this paper, we describe the development and application of a simple microfluidic device for in vitro irritation tests of cosmetics. The device was fabricated with a three-compartment diffusion system to mimic a hen’s egg test-chorioallantoic membrane (HET-CAM) system. Human umbilical vein endothelial cells were cultured in the three compartments, and the tested substances were injected into the...
This work describes a microfludic cell culture device embedded with microstructured posts fabricated by a photolithography technique and a replica-molding technique. BALB/3T3 fibroblast cells were cultured inside the PDMS microfludic chip to form a confluent state, and an external pressure was applied to the top part of the microfluidic chip to remove the cells from the contact areas of the posts...
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