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In whole body PET scanners, extending the axial field of view (AFOV) can significantly increases the sensitivity. However, image axial resolution, which is an essential criterion in whole-body PET, may be especially affected by the depth of interaction (DOI) as the AFOV increases. In this paper, we use Monte Carlo simulations to find, in a long axial-FOV PET how DOI information affects the axial resolution...
Recently DOI detection technologies have been rapidly developed for pre-clinical and clinical PET systems. Lack of DOI detection capability will result in serious LOR location deviation and image resolution degradation due to the detector parallax effect. Based on theoretically analyzing the probability distribution function of the DOI information, this study proposed four analytical DOI estimation...
In previous work, we have developed a cost-effective small-animal SPECT imaging system by adding a multi-pinhole cylinder collimator into an animal PET scanner. To achieve high-quality reconstructed SPECT image, accurate geometrical calibration of the collimator is critical. The pinhole position in PET-scanner's coordinate system (PSC) could be factorized into two parts: pinhole position in collimator's...
In this study, animal SPECT imaging functionality was developed in Nucmed Inliview 3000 PET/SPECT/CT system with an elliptical-pinhole collimator in the shared PET/SPECT ring detector. The collimator was designed to allow simultaneous PET/SPECT dual-tracer imaging. It contains 5 pinhole rings with 10 pinholes per ring. The transverse plane of pinhole was designed to be elliptical to reduce the axial...
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