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We report 21 patients (12 males and 9 females), belonging to 20 families with the clinical and laboratory features of a distal myopathy of Miyoshi type. The main clinical features of these patients were: (1) onset in late adolescence or early adulthood (mean age 20.3 years), (2) early and predominant involvement of the posterior compartment muscles of legs, (3) marked elevation of serum CK (mean...
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