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Background: Preeclampsia is characterized by endothelial cell dysfunction, and lipid peroxidation and alterations of immune responses may be involved in the pathogenesis of this disease. The aim of the present study was to examine changes in plasma malondialdehyde (MDA) level, an indicator of lipid peroxidation, and adenosine deaminase (ADA) activity, as a marker of T-cell activation in preeclampsia,...
Objectives: To investigate the relation between plasma adenosine deaminase (ADA) activity and cytokine-producing T cells in preeclampsia. Design and methods: Plasma ADA activity and the proportions of cytokine-producing T cells were measured in peripheral blood of 28 women with normal pregnancies and preeclampsia. The proportion of CD4-positive T cells producing interferon-γ and interleukin-4 were...
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