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Mild photothermal therapy (mPTT) has emerged as a highly promising approach for tumor ablation. However, the heat‐induced overexpression of heat shock proteins (HSPs) limits its efficacy by increasing cellular temperature tolerance. Herein, a self‐catalytically enhanced mild PTT strategy that directly disrupts the structure of HSPs to restore tumor cell sensitivity is proposed. In the proof‐of‐concept...
Nanomaterials with enzyme‐mimicking properties, coined as nanozymes, are a promising alternative to natural enzymes owing to their remarkable advantages, such as high stability, easy preparation, and favorable catalytic performance. Recently, with the rapid development of nanotechnology and characterization techniques, single atom nanozymes (SAzymes) with atomically dispersed active sites, well‐defined...
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