Search results for: Tingting Cai

Items from 1 to 20 out of 33 results

article

Mutational landscape of head and neck cancer and cervical cancer in Chinese and Western population

Qunxing Li, Genhai Zhu, Lizao Zhang, Binghui Zeng, more

Background We aimed to unbiasedly map the genetic mutation profile of HNSC and CESC associated with HPV status in the Chinese population (SYSU‐cohort) and compare them with Western population (TCGA‐cohort). Methods Fifty‐one HNSC patients (SYSU‐HNSC) and 38 CESC patients (SYSU‐CESC) were enrolled in this study. Genomic alterations were examined, and the profile was produced using the YuanSuTM450...

article

Depression with obstructive sleep apnea lead to high cardiovascular disease morbidity/all‐cause mortality: Findings from the SHHS cohort

Hui Liu, Wanda Peng, Lin Zhou, Yi Shen, more

Journal of Sleep Research > 32 > 4 > n/a - n/a

The aim of this study is to explore the association between depression and obstructive sleep apnea, and cardiovascular disease morbidity/all‐cause mortality using Sleep Heart Health Study data. This post hoc analysis of a prospective study used patient data from the Sleep Heart Health Study conducted between 1995 and 1998. The association between depression and obstructive sleep apnea, and cardiovascular...

article

Control of root‐to‐shoot long‐distance flow by a key ROS‐regulating factor in Arabidopsis

Tianling Jin, Huiyan Wu, Zhuying Deng, Tingting Cai, more

Plant, Cell & Environment > 45 > 8 > 2476 - 2491

Inter‐tissue communication is instrumental to coordinating the whole‐body level behaviour for complex multicellular organisms. However, little is known about the regulation of inter‐tissue information exchange. Here we carried out genetic screens for root‐to‐shoot mobile silencing in Arabidopsis plants with a compromised small RNA‐mediated gene silencing movement rate and identified radical‐induced...

article

Cover Image

Tianling Jin, Huiyan Wu, Zhuying Deng, Tingting Cai, more

Plant, Cell & Environment > 45 > 8 > i - i

The front cover image is based on the Research Article Control of root‐to‐shoot long‐distance flow by a key ROS‐regulating factor in Arabidopsis by Tianlin Jin et al., https://doi.org/10.1111/pce.14375.

article

Phase I clinical trial of HC‐1119 soft capsule in Chinese healthy adult male subjects: Pharmacokinetics and safety of single‐dose proportionality and effects of food

Haiping Ma, Weidong Xu, Jin Ni, Naping Zhao, more

The Prostate > 82 > 2 > 276 - 285

Background Preclinical studies showed that HC‐1119, a deuterated version of enzalutamide, could competitively inhibit androgen binding to androgen receptor by blocking the transmission of androgen receptor signaling pathway as enzalutamide, inducing apoptosis of prostate cancer cells and reducing the proliferation of prostate cancer cells. Animal pharmacokinetic studies also show that deuterization...

article

Accurate prediction of relative binding affinities of a series of HIV‐1 protease inhibitors using semi‐empirical quantum mechanical charge

Cheng Peng, Jinan Wang, Zhijian Xu, Tingting Cai, more

Journal of Computational Chemistry > 41 > 19 > 1773 - 1780

A major challenge in computer‐aided drug design is the accurate estimation of ligand binding affinity. Here, a new approach that combines the adaptive steered molecular dynamics (ASMD) and partial atomic charges calculated by semi‐empirical quantum mechanics (SQMPC), namely ASMD‐SQMPC, is suggested to predict the ligand binding affinities, with 24 HIV‐1 protease inhibitors as testing examples. In...

article

An improved hardening-damage creep model of lean coal: a theoretical and experimental study

Tingting Cai, Zengchao Feng, Yulong Jiang

Arabian Journal of Geosciences > 2018 > 11 > 20 > 1-12

Creep is an important rheological behavior of coal, impacting pillar stability, gateway support performance, and construction costs in underground mining. It is of great significance to study the creep mechanism of coal to prevent creep failure. In this paper, uniaxial compressive creep tests of raw lean coal under multiple stages are conducted, the increasing instantaneous elastic modulus and decreasing...

article

Anisotropy Characteristics of Stress Relaxation in Coal: An Improved Fractional Derivative Constitutive Model

Tingting Cai, Zengchao Feng, Yulong Jiang, Dong Zhao, more

Rock Mechanics and Rock Engineering > 2019 > 52 > 2 > 335-349

To study the anisotropy characteristics of coal during stress relaxation, a series of uniaxial compressive stress relaxation experiments are conducted on samples cut perpendicular and parallel to bedding. Some conclusions are as follows: (1) the stress of the specimens undergoes rapid relaxation, transient relaxation and steady relaxation, approximately represented with a negative exponential law,...

article

The effect of corn varieties on the production of fiber-reinforced high-density polyethylene composites

Bo Chen, Zhangfeng Luo, Tingting Cai, Di Cai, more

Biomass Conversion and Biorefinery > 2018 > 8 > 4 > 953-963

In this study, four different varieties of corn fibers were used as the reinforcing phase to produce corn fiber polyethylene composites (CFPC). Parameters including the chemical composition, performances of the corn fibers, and the mechanical properties, physical properties, and stabilities of the CFPCs were compared and evaluated. Generally, the CFPC’s properties were greatly influenced by the chemical...

article

Isothermal methane adsorption experiments at different temperature stages using the monolayer adsorption principle

Dong Zhao, Tingting Cai, Dong Zhou, Zengchao Feng

Arabian Journal of Geosciences > 2018 > 11 > 9 > 1-9

Isothermal methane adsorption methods are widely used in CBM and shale gas reservoirs; it is related to gas content. Adsorption volume is not only an important parameter for evaluating the characteristics of coal but can also provide a basis for adsorption capacity calculations. Thus, apparent and absolute adsorption volumes were introduced in this study and calculations of adsorption volume were...

article

Clock represses preadipocytes adipogenesis via GILZ

Zhu Zhu, Lirong Xu, Tingting Cai, Gongsheng Yuan, more

Journal of Cellular Physiology > 233 > 8 > 6028 - 6040

Adiposity is a worldwide health threat that needs to be prevented. Circadian gene Clock (circadian locomotor output cycles kaput) is closely correlated to adiposity; for example, weight gain, adipocytes size expansion, and serum lipid level rise in Clock^Δ19 mice compared to C57BL/6J mice. However, the precise role of Clock during adipogenic differentiation is unknown. Herein, the circadian gene Clock...

article

Master‐slave synchronization for coupled neural networks with Markovian switching topologies and stochastic perturbation

Jun Zhou, Tingting Cai, Wuneng Zhou, Dongbing Tong

International Journal of Robust and Nonlinear Control > 28 > 6 > 2249 - 2263

In this paper, the master‐slave synchronization for coupled neural networks with Markovian jumping topology and stochastic perturbation is discussed. Based on a graph theory, the ergodic property of the Markovian chain, and the strong law of the large numbers for local martingales, several sufficient conditions are established to ensure the almost sure exponential synchronization or asymptotic synchronization...

article

Decreased functional connectivity and disrupted neural network in the prefrontal cortex of affective disorders: A resting-state fNIRS study

Huilin Zhu, Jie Xu, Jiangxue Li, Hongjun Peng, more

Journal of Affective Disorders > 2017 > 221 > C > 132-144

Affective disorders (AD) have been conceptualized as neural network-level diseases. In this study, we utilized functional near infrared spectroscopy (fNIRS) to investigate the spontaneous hemodynamic activities in the prefrontal cortex (PFC) of the AD patients with or without medications.42 optical channels were applied to cover the superior frontal gyrus (SFG), middle frontal gyrus (MFG), and inferior...

article

Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells

Changpo Lin, Xiao Tang, Lirong Xu, Ruizhe Qian, more

Lipids in Health and Disease > 2017 > 16 > 1 > 1-8

Background The clock genes are involved in regulating cardiovascular functions, and their expression disorders would lead to circadian rhythm disruptions of clock-controlled genes (CCGs), resulting in atherosclerotic plaque formation and rupture. Our previous study revealed the rhythmic expression of clock genes were attenuated in human plaque-derived vascular smooth muscle cells (PVSMCs), but failed...

chapter

Research on a tunable consistency strategy of the distributed database

Chaozhi Yang, Tingting Cai, Zhihuai Li

2017 4th International Conference on Information, Cybernetics and Computational Social Systems (ICCSS) > 533 - 538

2017 4th International Conference on Information, Cybernetics and Computational Social Systems (ICCSS)

This paper proposes a Tunable Consistency Strategy(TCS) of the Distributed Databases. The TCS can divide the consistency dynamically for different requests. A request scheduling layer was added in the TCS to schedule different requests according to user's demand. The TCS can coordinate the consistency level dynamically and ensure the security of its data.

article

The Circadian Gene Clock Regulates Bone Formation Via PDIA3

Gongsheng Yuan, Bingxuan Hua, Yang Yang, Lirong Xu, more

Journal of Bone and Mineral Research > 32 > 4 > 861 - 871

The expression patterns of clock‐controlled genes (ccgs) are regulated by circadian rhythm, which is a major regulatory and physiological mechanism tied to the solar day. Disruptions in circadian rhythm contribute to the development of cardiovascular diseases, cancer, metabolic syndromes, and aging. It has been reported that bone remodeling is also regulated by circadian rhythm. However, the molecular...

article

Surface chemistry and catalytic performance of amorphous NiB/Hβ catalyst for n-hexane isomerization

Jinshe Chen, Tingting Cai, Xiaohui Jing, Lijun Zhu, more

Applied Surface Science > 2016 > 390 > C > 157-166

The amorphous NiB nanoparticles were synthesized and a novel type of NiB/Hβ catalyst was prepared for the isomerization of n-hexane. The optimum preparation conditions were investigated and the effect of preparation conditions on the surface chemistry information of catalysts was characterized by XRD, N₂ sorption studies, XPS, TPD and other related means. It was demonstrated that the loading amounts...

chapter

Neural correlates of stereoscopic depth perception: A fNIRS study

Huilin Zhu, Tingting Cai, Jie Xu, Shijing Wu, more

2016 Progress in Electromagnetic Research Symposium (PIERS) > 4442 - 4446

2016 Progress in Electromagnetic Research Symposium (PIERS)

The aim of the present study was to explore the brain region correlated with stereoscopic depth perception with different degree of binocular disparities. fNIRS was used to measure the neural activity of the occipital cortex induced by random-dot stereogram (RDS) with disparities from 0.1° to 1.5° and analyzed the strength and activation pattern from participants with left and right eyedness. Results...

article

Study on microstructural changes of coal after methane adsorption

Zengchao Feng, Dong Zhou, Yangsheng Zhao, Tingting Cai

Journal of Natural Gas Science and Engineering > 2016 > 30 > C > 28-37

This study analyzes the microstructure and deformation rule after methane adsorption on coal by scanning electron microscopy (SEM) and computed tomography (CT) scanning of microscopic coal samples. Studies have shown that coal is a natural rock composed of vitrinite coal matrix and clay mineral. After methane adsorption, coal undergoes non-uniform expansion deformation. This occurrence prompts coal...

article

AMR Steganalysis Based on the Probability of Same Pulse Position

Yanzhen Ren, Tingting Cai, Ming Tang, Lina Wang

IEEE Transactions on Information Forensics and Security > 2015 > 10 > 9 > 1801 - 1811

This paper presents a method for detection of adaptive multirate (AMR) audio steganography. AMR audio codec is an audio data compression scheme optimized for speech coding, and widely used in some mobile telecommunications system. The AMR audio steganography schemes are emerging recently and they embed secret messages by modifying the nonzero pulse positions which are determined by fixed codebook...

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INFONA - science communication portal

Search results for: Tingting Cai

Mutational landscape of head and neck cancer and cervical cancer in Chinese and Western population

Depression with obstructive sleep apnea lead to high cardiovascular disease morbidity/all‐cause mortality: Findings from the SHHS cohort

Control of root‐to‐shoot long‐distance flow by a key ROS‐regulating factor in Arabidopsis

Cover Image

Phase I clinical trial of HC‐1119 soft capsule in Chinese healthy adult male subjects: Pharmacokinetics and safety of single‐dose proportionality and effects of food

Accurate prediction of relative binding affinities of a series of HIV‐1 protease inhibitors using semi‐empirical quantum mechanical charge

An improved hardening-damage creep model of lean coal: a theoretical and experimental study

Anisotropy Characteristics of Stress Relaxation in Coal: An Improved Fractional Derivative Constitutive Model

The effect of corn varieties on the production of fiber-reinforced high-density polyethylene composites

Isothermal methane adsorption experiments at different temperature stages using the monolayer adsorption principle

Clock represses preadipocytes adipogenesis via GILZ

Master‐slave synchronization for coupled neural networks with Markovian switching topologies and stochastic perturbation

Decreased functional connectivity and disrupted neural network in the prefrontal cortex of affective disorders: A resting-state fNIRS study

Intracellular high cholesterol content disorders the clock genes, apoptosis-related genes and fibrinolytic-related genes rhythmic expressions in human plaque-derived vascular smooth muscle cells

Research on a tunable consistency strategy of the distributed database

The Circadian Gene Clock Regulates Bone Formation Via PDIA3

Surface chemistry and catalytic performance of amorphous NiB/Hβ catalyst for n-hexane isomerization

Neural correlates of stereoscopic depth perception: A fNIRS study

Study on microstructural changes of coal after methane adsorption

AMR Steganalysis Based on the Probability of Same Pulse Position

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