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Prognostic factors can help clinicians and patients when deciding a treatment plan. Patients in the best prognostic groups can be considered for more intensive or experimental therapy. Alternatively, patients in the best prognostic groups might prefer a period of observation prior to commencement of therapy. For patients with mesothelioma prognostic factors are potentially especially important because...
The incidence of malignant pleural mesothelioma (MPM) is increasing. Treatment options are limited, although recently published data have offered cause for optimism. We reported a response rate of 24% with low toxicity for single agent vinorelbine (Steele JP, Shamash J, Evans MT, Gower NH, Tischkowitz MD, Rudd RM. J Clin Oncol 2000;18:3912–7). Here we report a phase II trial of vinorelbine with oxaliplatin...
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