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In this paper, a new strategy is proposed for measuring the cell adhesion force by using a nanofork and a line-patterned substrate. The nanofork has three tines which resembles the appearance of a normal fork. In order to effectively implement the nanofork, a special design substrate, known as line-patterned (LP) substrate, is required. The spaces between the line structures on the substrate provide...
Cell-cell adhesion force is important for cell activities. In this paper, a novel cell-cell adhesion force measurement method using nano picker was proposed based on the nanorobotic manipulation system inside an environmental scanning electron microscopy (ESEM). The nano picker was fabricated from atomic force microscopy(AFM) cantilever by focused ion beam(FIB) etching. The spring constant of the...
In this paper, single cell adhesion force was measured using a nanofork. The nanofork was used to pick-up a single cell on a line-patterned substrate inside ESEM. The line-patterned substrate was used to provide small gaps between the single cells and the substrate. Therefore, the nanofork could be inserted through these gaps in order to successfully pick-up a single cell. Adhesion force was measured...
We performed in-situ single cell (W303) manipulation with force measurement inside the environment-SEM. The mechanical end effector was fabricated from a commercial AFM cantilever by FIB etching. The end effector was assembled to the nanorobotic manipulation system which can realize controlling the position at the nanometer scale. The releasing, sliding and rolling of single cell on a substrate were...
The possibility of realizing linear magnetic recording systems over 15 Gb/in2 recording density has been shown in our test with newly developed metal particulate (MP) tape using 35-nm-size fine metal particles and a GMR head designed for hard disk drive (HDD). It was done under a read-track-base calculation with the following media: magnetic layer thickness =60 nm, surface roughness Ra=2.0 nm.
Carbon nanotubes have been used as building blocks for assembly of nanostructures and nanodevices. Therefore, the interaction between the carbon nanotube and the environment is important. Interaction forces which were mainly consisted of van der Waals forces between a single multi-walled carbon nanotube tip and a gold surface were investigated and measured with an atomic force microscope cantilever...
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