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Self‐Boosting Vaccination
In article number 2207892, Xiang Gao, Bo Liu, Jing Gao, and co‐workers propose a pulsatile antigen released core‐shell microparticle namely LbL/MPs to achieve self‐boosting vaccination after single‐injection and to simulate multi‐injection immunization. LbL/MPs show multiple antigen release characteristics and can effectively induce immune response. The core‐shell microstructure...
Vaccination is among the most effective ways to prevent infectious diseases. Subunit vaccines are safe but usually require multiple booster shots, which may lead to immunity loss and economic consume. In this study, a self‐boosting vaccine is developed based on the pulsatile release of antigen from the core–shell microparticle after single‐injection immunization. Self‐healing technology applied to...
The solid‐state conversion of amorphous carbon into graphene is extremely difficult, but it can be achieved in the friction experiments that induce macroscale superlubricity. However, the underlying conversion mechanisms remain elusive. Here, the friction experiments with Cu nanoparticles and (non‐hydrogen (H) or H) a‐C in vacuum, show the H‐induced conversion of mechanical to chemical wear, resulting...
Herein, structural superlubricity, a fascinating phenomenon where the friction is ultralow due to the lateral interaction cancellation resulted from incommensurate contact crystalline surfaces, is reviewed. Various kinds of nano‐ and microscale materials such as 2D materials, metals, and compounds are used for the fabrication. For homogeneous frictional pairs, superlow friction forces exist in most...
Nanotechnology employs multifunctional engineered materials in the nanoscale range that provides many opportunities for translational stem cell research and therapy. Here, a cell‐penetrating peptide (virus‐1 transactivator of transcription)–conjugated, porous silicon nanoparticle (TPSi NP) loaded with the Wnt3a protein to increase both the cell survival rate and the delivery precision of stem cell...
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