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ObjectiveTo examine the effect of carbamazepine on the single oral dose pharmacokinetics of etizolam.MethodsEleven healthy male volunteers received carbamazepine 200 mg/day or placebo for 6 days in a double-blind, randomized, crossover manner, and on the sixth day they received a single oral 1-mg dose of etizolam. Blood samplings and evaluation of psychomotor function by the Digit Symbol Substitution...
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