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Tissue-like cultures of LT97 human colonic adenoma cells were produced by plating on reconstructed connective tissue supports (CTR) containing colon-associated fibroblasts to form mucosal monolayers and polyp-like structures closely resembling the in vivo situation. Tight cell–cell contacts and a high density of desmosomes were observed in 93.8±3.5% of the section area for CTR cultures, but only in...
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