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We analyzed the transferrin (TF) and apolipoprotein E (APOE) genotypes of 164 probable Alzheimer's disease (AD) patients and 239 cognitively normal elderly controls in Koreans. We failed to detect a significant difference in genotypic frequencies and allelic frequencies of the TF polymorphism between the AD group and control group (P>0.1 by Chi square test). The frequency of the TF C2 variant did...
We analyzed the aplolipoprotein E (APOE) genotypes of 110 probable AD patients and 226 cognitively normal controls in Koreans. The APOE 4 allele was more prevalent in both early- and late-onset AD patients (P<0.01) than in controls. The odds for the APOE 4-heterozygous subjects were 2.7 (95% CI=1.6-4.5), and those for the APOE 4-homozygous subjects were 17.4 (95% CI=2.0-147.3). But the odds...
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