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Aim: Thedevelopment of Type2 diabetes mellitus (T2DM) has been recognized to beassociated with a combination of pancreatic β-cell dysfunction and insulin resistance. Nuclear factor-κB (NF-κB) has been recognized as one central mediator in the reaction of inflammation and proapoptotic event in β-cells. A functional polymorphism at the codon 55 (methionine to valine; A163G) of the small ubiquitin-like...
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