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We demonstrate an efficient method for cancer cell capture via cell line-specific protein deposition on nanoporous surface in microfluidic channels. Specifically, anti-epithelial cell adhesion molecules (EpCAM) were microcontact printed onto nanoporous silica substrate with optimal pore size of 4nm, porosity of 52.4±0.2%, and thin film thickness of 130±0.5nm. SkBr3, Colo205, and MDA-MB-435 cancer...
This paper presents the fabrication, characterization and imaging results of a wide-scanning, low voltage driven and electrical discharge machining (EDM) process fabricated stainless steel micro-scanner based real-time confocal hyperspectral fluorescence microscope for skin cancer detection.
We present the design of hollow near-field scanning microscope (NSOM) probe with nanogratings-on-tip to transport and concentrate localized surface plasmonic polariton (SPP) wave. By adding nano-grooves started from the intensity-maximum locations of lowest transmission mode and with pitch period supporting the metal-air interface SPP mode, the power throughput is increased at over 530 times comparing...
We introduce a novel scanning ldquonanophotonicrdquo microscope through monolithic integration of a nanoscale LED (Nano-LED) on a silicon cantilever. We review two recent trends of incorporating miniature light sources on the scanning probes for near-field scanning optical microscopy: one is to attach fluorephores at the tip to define a small light source, while the other is to integrate an LED and...
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