Wyniki wyszukiwania dla: Elizabeth A. Stewart

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Vaginal bromocriptine improves pain, menstrual bleeding and quality of life in women with adenomyosis: A pilot study

Johanna K. Andersson, Zaraq Khan, Amy L. Weaver, Lisa E. Vaughan, więcej

Acta Obstetricia et Gynecologica Scandinavica > 98 > 10 > 1341 - 1350

Introduction Adenomyosis is a benign uterine disease where endometrial glands and stroma are found within the myometrium surrounded by an area of hypertrophic myometrium. Symptomatology includes heavy menstrual bleeding and pelvic pain. The pathogenesis of adenomyosis is not known; however, animal models have shown increased uterine concentration of prolactin as a risk factor. Prolactin acts as a...

artykuł

The Comparing Options for Management: PAtient-centered REsults for Uterine Fibroids (COMPARE-UF) registry: rationale and design

Elizabeth A. Stewart, Barbara L. Lytle, Laine Thomas, Ganesa R Wegienka, więcej

American Journal of Obstetrics and Gynecology > 2018 > 219 > 1 > 95.e1-95.e10

Uterine fibroids are common in premenopausal women, yet comparative effectiveness research on uterine fibroid treatments is rare.The purpose of this study was to design and establish a uterine fibroid registry based in the United States to provide comparative effectiveness data regarding uterine fibroid treatment.We report here the design and initial recruitment for the Comparing Options for Management:...

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Adverse childhood experiences and adult abuse are predictors of hysterectomy and oophorectomy

Liliana Gazzuola Rocca, Carin Y. Smith, Elizabeth A. Stewart, Walter A. Rocca

Maturitas > 2017 > 106 > C > 95-96

artykuł

Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans

Jacklyn N. Hellwege, Janina M. Jeff, Lauren A. Wise, C. Scott Gallagher, więcej

Human Genetics > 2017 > 136 > 11-12 > 1497-1498

The article “A multi-stage genome-wide association study of uterine fibroids in African Americans”, written by Jacklyn N. Hellwege, was originally published Online First without open access. After publication in volume 136, issue 10, page 1363–1373 the author decided to opt for Open Choice and to make the article an open access publication. Therefore, the copyright of the article has been changed...

artykuł

Uterine fibroids: correlations between MRI appearance and stiffness via magnetic resonance elastography

Danielle E. Jondal, Jin Wang, Jun Chen, Krzysztof R. Gorny, więcej

Abdominal Radiology > 2018 > 43 > 6 > 1456-1463

Rationale and objectives Magnetic resonance elastography has proven to be a valuable tool in the diagnosis of liver fibrosis, breast and cervical cancer, but its application in uterine fibroids requires further characterization. The aim of the present study was to examine the relationship between uterine fibroid stiffness by MRE and MR imaging characteristics. Materials and methods An IRB-approved,...

artykuł

A multi-stage genome-wide association study of uterine fibroids in African Americans

Jacklyn N. Hellwege, Janina M. Jeff, Lauren A. Wise, C. Scott Gallagher, więcej

Human Genetics > 2017 > 136 > 10 > 1363-1373

Uterine fibroids are benign tumors of the uterus affecting up to 77% of women by menopause. They are the leading indication for hysterectomy, and account for $34 billion annually in the United States. Race/ethnicity and age are the strongest known risk factors. African American (AA) women have higher prevalence, earlier onset, and larger and more numerous fibroids than European American women. We...

artykuł

Elagolix for the management of heavy menstrual bleeding associated with uterine fibroids: results from a phase 2a proof-of-concept study

David F. Archer, Elizabeth A. Stewart, Rita I. Jain, Robert A. Feldman, więcej

Fertility and Sterility > 2017 > 108 > 1 > 152-160.e4

To evaluate the safety and efficacy of elagolix vs. placebo and elagolix with low-dose E₂/progestogen add-back therapy.Proof-of-concept, dose-ranging, multiple-cohort study.Clinics.Premenopausal women with fibroids and heavy menstrual bleeding (menstrual blood loss [MBL] >80 mL per cycle).Three months' treatment with elagolix alone: 100 mg twice daily (BID), 200 mg BID, 300 mg BID, 400 mg once...

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Hereditary leiomyomatosis and renal cell cancer: Cutaneous lesions & atypical fibroids

Pietro Bortoletto, Jennifer L. Lindsey, Liping Yuan, Bradley J. Quade, więcej

Case Reports in Women's Health > 2017 > 15 > C > 31-34

To report a diagnosis of hereditary leiomyomatosis and renal cell cancer (HLRCC) syndrome following initial presentation with multiple cutaneous lesions.Case report.N/A.Academic tertiary care center.27-year-old nulligravid woman who presented with multiple red-brown lesions on her skin found to have cutaneous and uterine leiomyoma.Biopsy of cutaneous lesions and fertility sparing robot-assisted laparoscopic...

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Periprocedural outcomes comparing fibroid embolization and focused ultrasound: a randomized controlled trial and comprehensive cohort analysis

Emily P. Barnard, Ahmed M. AbdElmagied, Lisa E. Vaughan, Amy L. Weaver, więcej

American Journal of Obstetrics and Gynecology > 2017 > 216 > 5 > 500.e1-500.e11

Uterine fibroids are a common problem for reproductive-aged women, yet little comparative effectiveness research is available to guide treatment choice. Uterine artery embolization and magnetic resonance imaging–guided focused ultrasound surgery are minimally invasive therapies approved by the US Food and Drug Administration for treating symptomatic uterine fibroids. The Fibroid Interventions: Reducing...

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Ultrasound-Diagnosed Uterine Fibroids Are Not Associated with Creativity Scores by Standardized Testing

Elliott G. Richards, Melissa S. Richards, Elizabeth A. Stewart, Shannon K. Laughlin-Tommaso

EXPLORE: The Journal of Science and Healing > 2016 > 12 > 6 > 440-442

artykuł

Accelerated Accumulation of Multimorbidity After Bilateral Oophorectomy: A Population-Based Cohort Study

Walter A. Rocca, Liliana Gazzuola-Rocca, Carin Y. Smith, Brandon R. Grossardt, więcej

Mayo Clinic Proceedings > 2016 > 91 > 11 > 1577-1589

To study the association between bilateral oophorectomy and the rate of accumulation of multimorbidity.In this historical cohort study, the Rochester Epidemiology Project records-linkage system was used to identify all premenopausal women who underwent bilateral oophorectomy before age 50 years between January 1, 1988, and December 31, 2007, in Olmsted County, Minnesota. Each woman was randomly matched...

artykuł

Fibroid interventions: reducing symptoms today and tomorrow: extending generalizability by using a comprehensive cohort design with a randomized controlled trial

Ahmed M. AbdElmagied, Lisa E. Vaughan, Amy L. Weaver, Shannon K. Laughlin-Tommaso, więcej

American Journal of Obstetrics and Gynecology > 2016 > 215 > 3 > 338.e1-338.e18

Uterine fibroids are an important source of morbidity for reproductive-aged women. Despite an increasing number of alternatives, hysterectomies account for about 75% of all fibroid interventional treatments. Evidence is lacking to help women and their health care providers decide among alternatives to hysterectomy. Fibroid Interventions: Reducing Symptoms Today and Tomorrow (NCT00995878, clinicaltrials...

rozdział

Focused Ultrasound for Tumor Ablation

Clare Tempany, Nathan MacDonold, Elizabeth A. Stewart, Kullervo Hynynen

Tumor Ablation > Methods of Ablation > 273-284

This chapter reviews the basic principles of focused ultrasound therapy. The physical principles are discussed and explained. The technical requirements and instrumentation used are illustrated. The critical value of using magnetic resonance (MR) as an image guidance method for planning, delivering, and monitoring this form of ablation therapy is reviewed, and its application in uterine leiomyomas...

artykuł

Expression of Toll-like receptors in human retinal and choroidal vascular endothelial cells

Elizabeth A. Stewart, Ruoxin Wei, Matthew J. Branch, Laura E. Sidney, więcej

Experimental Eye Research > 2015 > 138 > Complete > 114-123

Toll-like receptors (TLRs) are a family of proteins that initiate the innate immune response in reaction to invading microbes. Studies confirm the expression of TLRs in a variety of ocular tissues and cells, and it has also been suggested that selected TLRs may be associated with geographic atrophy and neovascularisation in age-related macular degeneration, diabetic retinopathy and other vascular...

artykuł

Effect of menses on standardized assessment of sexual dysfunction among women with uterine fibroids: a cohort study

Shannon K. Laughlin-Tommaso, Bijan J. Borah, Elizabeth A. Stewart

Fertility and Sterility > 2015 > 104 > 2 > 435-439

To determine if assessment of sexual dysfunction by the Female Sexual Function Index (FSFI) is related to whether the FSFI is administered during or between menses, in women with symptomatic uterine fibroids.Prospective cohort.Academic medical centers.Premenopausal women who had symptomatic uterine fibroids and were enrolled in fibroid treatment trials.Administration of FSFI during and between menses...

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Cutaneous and Uterine Leiomyomas

Elizabeth A. Stewart, Cynthia C. Morton

Mayo Clinic Proceedings > 2015 > 90 > 7 > 990

artykuł

Preconception risk stratification before fertility care

Kristi S. Borowski, Brian C. Brost, Elizabeth A. Stewart, Eileen J. Hay, więcej

Fertility and Sterility > 2015 > 104 > 1 > 28-31

artykuł

Incidence of Additional Treatments in Women Treated with MR-Guided Focused US for Symptomatic Uterine Fibroids: Review of 138 Patients with an Average Follow-up of 2.8 Years

Krzysztof R. Gorny, Bijan J. Borah, Douglas L. Brown, David A. Woodrum, więcej

Journal of Vascular and Interventional Radiology > 2014 > 25 > 10 > 1506-1512

To assess long-term outcomes of magnetic resonance (MR)–guided focused ultrasound (US) treatments of uterine fibroids.A retrospective follow-up of 138 patients treated at a single institution between March 2005 and November 2011 was conducted. The patients were not part of a clinical study and were followed through retrospective review of their medical records and telephone interviews to assess additional...

artykuł

The health disparities of uterine fibroid tumors for African American women: a public health issue

Heba M. Eltoukhi, Monica N. Modi, Meredith Weston, Alicia Y. Armstrong, więcej

American Journal of Obstetrics and Gynecology > 2014 > 210 > 3 > 194-199

Uterine fibroid tumors (leiomyomas) are the most common benign pelvic tumors in women and are the major indication for hysterectomy. Fibroid tumors are more common and more severe among African American women. Although this disease disproportionately affects the African American population, we understand little about what causes the disparity. Fibroid tumors should be considered a public health issue,...

artykuł

Unilateral oophorectomy results in compensatory follicular recruitment in the remaining ovary at time of ovarian stimulation for in vitro fertilization

Zaraq Khan, Ravi P. Gada, Zaid M. Tabbaa, Shannon K. Laughlin-Tommaso, więcej

Fertility and Sterility > 2014 > 101 > 3 > 722-727

To assess the effect of unilateral oophorectomy (UO) by assessing ovarian reserve (OVR) and the response to gonadotropin stimulation in women with UO undergoing in vitro fertilization (IVF) compared with the response of the ipsilateral ovary of women without UO.Historical cohort study.Academic fertility clinic.Fifty-one women with single ovary compared with a referent group with both ovaries in a...

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