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Mouse embryonic stem cells (mESCs) are characterized by their self‐renewal and pluripotency and are capable of differentiating into all three germ layers. For this reason, mESCs are considered a very important model for stem cell research and clinical applications in regenerative medicine. The pre‐mRNA processing factor 4 (PRPF4) gene is known to have a major effect on pre‐mRNA splicing and is also...
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