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Although the major SARS‐CoV‐2 omicron lineages share over 30 non‐synonymous substitutions in the spike glycoprotein, they show several unique mutations that were acquired after their ancestral split. One of the most intriguing mutations associated with BA.1 is the presence of the inserted tripeptide Glu‐Pro‐Glu within the N‐terminal domain, at a site that had previously independently acquired short...
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