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Progression of astrocytic tumors is, in part, related to their dysregulated autophagy capacity. Recent evidence indicates that upstream autophagy signaling events can be triggered by MT1‐MMP, a membrane‐bound matrix metalloproteinase that contributes to the invasive phenotype of brain cancer cells. The signaling functions of MT1‐MMP require its intracellular domain, and recent identification of MTCBP‐1,...
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