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Abstract. The activation of mitogen-activated protein kinase (MAPK) pathways in the heart, for instance by 1-adrenoceptor agonists and endothelin-1, has primarily been associated with cellular growth regulation. Here we have investigated a possible role of MAPK pathways in the inotropic and chronotropic effects of adrenoceptor agonists and endothelin-1 in isolated rat left and right atria. Inotropic...
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