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The development of explosives detection technologies has increased significantly over the years as environmental and national security agencies implement tighter pollution control measures and methods for improving homeland security. 2, 4, 6-Trinitrotoluene (TNT), known primarily as a component in munitions, has been targeted for both its toxicity and carcinogenic properties that if present at high...
A reversed-displacement immunosensor to detect the explosive, 2,4,6-trinitrotoluene (TNT) using a chemically modified borosilicate glass microcapillary is described. The inner core of a glass microcapillary was modified with 3-aminopropyltriethoxysilane and functionalized with the TNT analog, trinitrobenzene sulfonic acid (TNBSA). A Cy5-labeled anti-TNT antibody was incubated within the trinitrobenzene...
Reported in this study are the experimental design and results of an immunosensor for the detection of the explosive, 2,4,6-trinitrotoluene (TNT) in seawater using a reversed-displacement format. This reversed-displacement immunosensor methodology has successfully measured TNT in seawater by direct injection, eliminating the need for preconcentration or pretreatment of samples. A microcolumn containing...
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